Difference between serotonin syndrome (SS) and neurolept malignant syndrome (NMS):


in SS, a patient has neuromuscular hyperactivity (hyperreflexia, myoclonus, ocular clonus) instead of bradykinesia and rigidity in NMS.

Fluoxetine has a half-life of 5 weeks, so, before switching to MAOi, wait for 5 weeks because it will cause serotonin syndrome.

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